Skin rash in a woman with hairy cell leukaemia

Autores/as

  • Vitorino Modesto dos Santos Armed Forces Hospital
  • Gustavo Bettarello Armed Forces Hospital
  • Fernando Henrique de Paula Catholic University Medical Course
  • Rodrigo Aires de Castro Armed Forces Hospital
  • Eula Leisle Braz Lima Armed Forces Hospital
  • Thomas Edison Cintra Osterne Catholic University Medical Course

Resumen

Context: Skin eruptions associated with hairy cell leukaemia have been scarcely described.
Case report: A 65-year-old woman with admission tests showing normal haemoglobin, severe neutropenia, and mild thrombocytopenia. The diagnosis of this leukaemia was based on typical hairy cells in bone marrow, in addition to immunohistochemistry, cell immunophenotype, and DBA4 marker. Administration of cladribine was followed by a generalized maculopapular rash and vesicles, which improved soon after the suspension of that drug.
Conclusion: Skin eruptions associated to the use of cladribine occur in patients with hairy cell leukaemia, and may be underreported.

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Biografía del autor/a

Thomas Edison Cintra Osterne, Catholic University Medical Course

Context: Skin eruptions associated with hairy cell leukaemia have been scarcely described.
Case report: A 65-year-old woman with admission tests showing normal haemoglobin, severe neutropenia, and mild thrombocytopenia. The diagnosis of this leukaemia was based on typical hairy cells in bone marrow, in addition to immunohistochemistry, cell immunophenotype, and DBA4 marker. Administration of cladribine
was followed by a generalized maculopapular rash and vesicles, which improved soon after the suspension of that drug.
Conclusion: Skin eruptions associated to the use of cladribine occur in patients with hairy cell leukaemia,
and may be underreported.

Citas

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Publicado

2018-10-12

Cómo citar

dos Santos, V. M., Bettarello, G., Henrique de Paula, F., Aires de Castro, R., Braz Lima, E. L., & Cintra Osterne, T. E. (2018). Skin rash in a woman with hairy cell leukaemia. Revista De La Facultad De Ciencias Médicas (Quito), 34(1-2), 43-47. Recuperado a partir de http://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1056