Bioquímica de la Diabetes Gestacional
Resumen
La diabetes gestacional y sus graves consecuencias obstétricas constituyen una de las grandes patologías de la mujer durante su embarazo. Con este objetivo analizamos en el presente artículo en forma detallada las implicaciones bioquímicas que conlleva esta grave patología y que son los determinantes bioquímico-fisiopatológicos de las explicaciones médicas de los efectos clínicos observados durante el embarazo y en el recién nacido.
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Felig, P.: Maternal and fetal homeostasis in hu man pregnaney. Arn J Clin Nutr, 26: 988, 1973.
Rice, PA., Rourke, JE. et Nessitt, RE.: In vitro perfusión studies of the human placenta. Evi- dence against active glucose transport. Am. j. Obstet Gynecol, 133: 649, 1979.
Like, AA. and Orci, L.: Embi’yogenesis of the human pancreatic islots: a light and electrón mieroscopic study. Diabetes, 21: 511, 1972.
Felig, P.: Body fuel metabolism and diabetes mellitus in pregnaney. Med Clin North Am, 61: 43, 1977.
Gresham, EL., James, EJ. and Ray, JR.: Pro- duction and excretion of urea by the fetai lamb. Pediatrics, 50: 372, 1972.
Hull, Di and Elphick, MC.: Evidence for fatty acid transfer across the human placenta. In: Pregnancy metabolism diabetes and the fetus. Excerpta Medica, edit., Amsterdam, 71, 1979.
Kalhan, SE. and D’Angello, LJ.: Glucosa pro- duction in pregnant women at terme gestation. Source of glucose for human fetus. J Clin In- vest, 63: 388,1979.
Page, MA. and Williamson, DM.: Enzymes of ketonebody utilisation in human brain. Lancet ii, 66, 1971.
Tchobrontsky, C.: Le foetus et le nouveau-né de méres diabétique (diabéte insulino-depen- dant) Pathol Biol, 18: 533,1970.
Longbloet, PH.: Abnorinal infants and diabetic mothers. Lancet i: 994, 1980.
Whitsett, J. and Brownshcidle, CH.: Aspects oí placental structure and function in maternal diabetes. In: Merkátz IR, Adám PA (éds), The diabetic; pregnancy—á—perinatal perspective. Grúrte & Stratton, edit. New York, 1979.
Pedersen, J . and Molsted—Pedersen, L .: Conge nital Malformations: the possible role of dia betes care outside pregnancy. In: Pregnancy metabolism, diabetes and the foetus. Giba Foundation Symposium 63, Excerpta Medica, edit, Amsterdam, 265, 1979.
Sadler, TW.: Effects of maternal diabetes on early embryogenesis: I. The teratogenic poten- tial of diabetic serum. Teratology, 21: 339, 1980.
Sosenko,IR.,Kizmiller,JL.,Loo,SW.,Blix,P., Rubenstein, AA. and Gabbay, KH.: The infant of diabetic mother: correlation of increased cord C—peptide levels with macrosomia and hypogluycemia. N Eng J Med, 16: 359, 1979.
Toorson, AV. and Hintz, RL.: Insulin receptor» in the newborn: increase in receptor affinity and number. N Eng J. Med, 17: 908, 1977.
Felig, P.: Maternal and fetal homeostasis in hu man pregnaney. Arn J Clin Nutr, 26: 988, 1973.
Rice, PA., Rourke, JE. et Nessitt, RE.: In vitro perfusión studies of the human placenta. Evi- dence against active glucose transport. Am. j. Obstet Gynecol, 133: 649, 1979.
Like, AA. and Orci, L.: Embi’yogenesis of the human pancreatic islots: a light and electrón mieroscopic study. Diabetes, 21: 511, 1972.
Felig, P.: Body fuel metabolism and diabetes mellitus in pregnaney. Med Clin North Am, 61: 43, 1977.
Gresham, EL., James, EJ. and Ray, JR.: Pro- duction and excretion of urea by the fetai lamb. Pediatrics, 50: 372, 1972.
Hull, Di and Elphick, MC.: Evidence for fatty acid transfer across the human placenta. In: Pregnancy metabolism diabetes and the fetus. Excerpta Medica, edit., Amsterdam, 71, 1979.
Kalhan, SE. and D’Angello, LJ.: Glucosa pro- duction in pregnant women at terme gestation. Source of glucose for human fetus. J Clin In- vest, 63: 388,1979.
Page, MA. and Williamson, DM.: Enzymes of ketonebody utilisation in human brain. Lancet ii, 66, 1971.
Tchobrontsky, C.: Le foetus et le nouveau-né de méres diabétique (diabéte insulino-depen- dant) Pathol Biol, 18: 533,1970.
Longbloet, PH.: Abnorinal infants and diabetic mothers. Lancet i: 994, 1980.
Whitsett, J. and Brownshcidle, CH.: Aspects oí placental structure and function in maternal diabetes. In: Merkátz IR, Adám PA (éds), The diabetic; pregnancy—á—perinatal perspective. Grúrte & Stratton, edit. New York, 1979.
Pedersen, J . and Molsted—Pedersen, L .: Conge nital Malformations: the possible role of dia betes care outside pregnancy. In: Pregnancy metabolism, diabetes and the foetus. Giba Foundation Symposium 63, Excerpta Medica, edit, Amsterdam, 265, 1979.
Sadler, TW.: Effects of maternal diabetes on early embryogenesis: I. The teratogenic poten- tial of diabetic serum. Teratology, 21: 339, 1980.
Sosenko,IR.,Kizmiller,JL.,Loo,SW.,Blix,P., Rubenstein, AA. and Gabbay, KH.: The infant of diabetic mother: correlation of increased cord C—peptide levels with macrosomia and hypogluycemia. N Eng J Med, 16: 359, 1979.
Toorson, AV. and Hintz, RL.: Insulin receptor» in the newborn: increase in receptor affinity and number. N Eng J. Med, 17: 908, 1977.
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Publicado
2017-06-16
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1.
Calle M. A, Mendoza V. M. Bioquímica de la Diabetes Gestacional. Rev Fac Cien Med (Quito) [Internet]. 16 de junio de 2017 [citado 8 de mayo de 2024];13(3-4):85-8. Disponible en: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/654
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