Salud mental y uso racional de litio en el Ecuador, un tema controversial
DOI:
https://doi.org/10.29166/ciencias_medicas.v42i1.1580Keywords:
lithium carbonate, bipolar disorder, depressive disorder, treatment-resistantAbstract
The use of lithium is as old as its history, generating in time detractor voices and as important defenders. In Ecuador, this controversy is not exempt from the use of lithium to treat bipolar disorder, suicidal events and as an adjuvant in cases of treatment-resistant depression, despite being a basic drug with proven efficacy in these pathologies. Adequate management and monitoring would avoid its substitution by drugs of greater cost, especially for the National Public Health System, which assists an important segment of the population with low economic resources.
Downloads
Metrics
References
Cade J. Lithium salts in the treatment of psychotic excitement. Med J Aust 1949; 2(10):349–52.
Corcoran RT, Page I. Lithium poisoning from the use of salt substitutes. JAMA 1949; 139(11):685–8.
Mármol F. Litio: 55 años de historia en el tratamiento del trastorno bipolar. Med Clin (Barc) 2006;127(5):189–95.
Cipriani A, Hawton K, Stockton S, Geddes JR. Lithium in the prevention of suicide in mood disorders:updated systematic review and meta-analysis. BMJ 2013; 3646:1–13.
Guzzetta F, Tondo L, Centorrino F, Baldessarini RJ. Lithium treatment reduces suicide risk in recurrent major depressive disorder. J Clin Psychiatry 2007; 68(3):380–3.
Lauterbach E, Felber W, Müller-Oerlinghausen B, Ahrens B, Bronisch T, Meyer T, et al. Adjunctive lithium treatment in the prevention of suicidal behaviour in depressive disorders: a randomised, placebo-controlled, 1-year trial. Acta Psychiatr Scand 2008; 118(6):469–79.
Consejo Nacional de Salud. Cuadro Nacional de Medicamentos Básicos y Registro Terapéutico. 9ed. Quito:Publiasesores Cía. Ltda; 2014. 894 p.
Consejo Nacional de Fijación y Revisión de Precios de Medicamentos de Uso y Consumo Humano. Resolución 10-2015 del Consejo Nacional de Fijación y Revisión de Precios de Medicamentos de Uso y Consumo Humano de fecha 19 de agosto de 2015 sesión Nro.637. 2015. p. 54.
Royal Pharmaceutical Society of Great Britain. British National Formulary 70. 70th ed. Pößneck: GGP Media GmbH; 2015. 1366 p.
Kennedy SH, Lam RW, Parikh S V., Patten SB, Ravindran A V. Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. J Affect Disord 2009; 117:S1–2.
NHS Sussex Partnership. Guidelines for the Prescribing and Monitoring of Inpatient Lithium Therapy.2017; 2–11.
Asamblea Nacional Constituyente. Constitución Política de la República del Ecuador. Libro incluye las reformas aprobadas en el Referéndum y Consulta Popular de 7 de mayo del 2011. 2008. 1-216 p.
Congreso Nacional. Ley Orgánica del Sistema Nacional de Salud. 2002. 13 p.
