Klatskin Tumor and Brain Metastasis in a Breast Cancer Patient: Case Report
DOI:
https://doi.org/10.29166/rfcmq.v45i1.2644Keywords:
Klatskin Tumor, Breast Neoplasms, Hemiplegia, Neoplasm MetastasisAbstract
Introduction: Breast cancer is the principal cause of death in women worldwide, classified based on the expression of estrogen receptor, progesterone, and ERBB2. Klatskin tumor is rare and originates in the bifurcation of the extrahepatic bile duct.
Case presentation: A 60 years old female patient diagnosed with stage IIIB breast cancer presents right hemiplegia secondary to metastatic brain injury, initially classified as neurocysticercosis. After one year and seven months, she developed cholestatic jaundice, whose clinical evaluation allows Klatskin tumor evidence through cholangioresonance.
Discussion: The present case is about a patient with multiple metastases secondary to breast cancer. Including, in the same way, a Klatskin tumor, which was discovered after a cholestatic syndrome.
Conclusions: Few cases in the literature register metastatic processes towards bile ducts originating from infiltrating ductal carcinoma; however, it is essential to report for clinical evidence and study of the literature.
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Akram M, Iqbal M, Daniyal M, Khan AU. Awareness and current knowledge of breast cancer. Biol Res. 2017;50(1):1–23.
OMS. Cáncer [Internet]. 2018 [cited 2020 Jul 9]. Available from: https://www.who.int/es/news-room/fact-sheets/detail/cancer
Yeo SK, Guan JL. Breast Cancer: Multiple Subtypes within a Tumor? Trends in Cancer. 2017;3(11):753–60.
Zhang X, Liu H. Klatskin Tumor: A Population-Based study of incidence and survival. Med Sci Monit [Internet]. 2019 [cited 2020 Jul 8];25:4503–12. Available from: /pmc/articles/PMC6597140/?report=abstract.
Furuse J. Orphanet: Tumor de Klatskin [Internet]. 2012 [cited 2020 Jul 9]. Available from: https://www.orpha.net/consor/cgi-bin/OC_Exp.php?lng=ES&Expert=99978
Hidalgo Méndez F. Colangiocarcinoma hiliar (tumor de Klatskin). Rev Clínica Med Fam. 2014;7(1):69–72.
Liu ZY, Sun JJ, He KW, Zhuo PY, Yu ZY. Primary or metastatic hepatic carcinoma? A breast cancer patient after adjuvant chemotherapy and radiotherapy postoperatively with intrahepatic cholangiocarcinoma and review of the literature. World J Surg Oncol [Internet]. 2016;14(1):10–3. Available from: http://dx.doi.org/10.1186/s12957-016-0943-0
Espinosa M. Cáncer de Mama. Rev Médica Sinerg. 2018;2(1):8–12.
Madrigal A, Mora B. Generalidades de Cáncer de Mama para Médico General. Rev Int Grup en Investig en Oncol. 2018;35(1):8.
Medina G. Clinical and prognostic characteristics of the molecular subtypes of breast cancer determined by immunohistochemistry. Arequipa, Peru. Rev Peru Med Exp Salud Publica. 2017;34(3):472–7.
Cacho B, Reyes G, Monroy A, Lorenzana N, Olvera E, Rodríguez J, et al. Manifestaciones neurológicas en pacientes con cáncer: más de 17,000 motivos de consulta. Rev Mex Neurocienc. 2016;17(2):1–110.
López D, Valle S, Ferrer AI, Coves J, Galán N, Gimeno J, et al. Complicaciones neurológicas del paciente con cáncer. Psicooncología. 2011 Jun;8(1):53–64.
Tirapu De Sagrario MG, Baleato González S, García Figueiras R, Coessens A. Metástasis biliares intraductales de carcinoma colorrectal: A propósito de 2 casos. Radiologia. 2014 Nov;56(6):e34–7.
Coletta M, Montalti R, Pistelli M, Vincenzi P, Mocchegiani F, Vivarelli M. Metastatic breast cancer mimicking a hilar cholangiocarcinoma: Case report and review of the literature. World J Surg Oncol. 2014 Dec;12(1).
Cochrane J, Schlepp G. Metastatic breast cancer to the common bile duct presenting as obstructive jaundice. Case Rep Gastroenterol. 2015 May;9(2):278–84.
Pérez-Reguera Gutiérrez A, De León Bojorge B, Goldberg J, Ortiz De La Peña J, Ortiz Hidalgo C. Pérez-Reguera GA y cols. Metástasis de carcinoma mamario lobulillar a vesícula biliar Metástasis de carcinoma mamario lobulillar a vesícula biliar. Estudio con inmunohistoquímica de receptores hormonales. Vol. 46. 2000.
Sánchez F, Falcón L, Hospital V, Rollán C, Nari GA, Viotto L, et al. Acta Gastroenterológica Latinoamericana. Acta Soc Argentina Gastroenterol. 2015;45(4).
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Copyright (c) 2020 Leslie Suntaxi-Basantes, Jenifer Cevallos T, Anabel Ramírez M, D Solange Medina, Dr. Edwin Efraín Cevallos Barrera
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