Cinética de la Infección con Leishmania Mexicana en Ratones Balb/c y C57BL/6 previamente Inmunizados con Factor Excretor
Abstract
La inmunización de ratones BALB/c y C57BL/6 (genéticamente sensibles y resistentes a la infección por Leishmania mexicana respectivamente) con factor excretor de Leishmania mexicana promueve el desarrollo de la infección. Guando los ratones mencionados son retados con dosis infectivas de promastigotes de Leishmania mexicana mexicana.
Los ratones BALB/c desarrollan la enfermedad en un período inicial más corto y con mayor intensidad en relación a los testigos (ratones BALB/e no vacunados). Los ratones C57BL/6, no logran controlar la enfermedad, desarrollando la forma crónica, frente al grupo testigo (ratones C57BL/6 n<? vacunados) que controla fácilmente la infección.
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References
1. Slutzky, G.M.; El Elon, J. y Greenblatt, C.: Leishmaniaí Excreted Factor: “Protein-Bound and Free Forms From Promastigote Cultures of Leishmania Trópica and Leishmania Donovan”. Infection and Inmunity 26: 916, 1979.
2. Schnur, L.F.: A. Zurkerman y Greenblatt, C.L.: “Leishmaniaí serotypes as distinguished by the gel diffusion of factors excreted in vitro and in vivo, lsr” . J.Med. Sci. 8:132, 1972.
3. Swtzky, G.M. y Greenblatt, C.L.: “Isolation of a Carbohidrate-Rich Inmunologically Active Factor from Cultures of Leishmania Trópica” Febs. Lett. 80:401, 1977.
4. El.-On, J., Schnur, L. y Greenblatt, C.L.: “Leishmania donovani: Physicochemical Inmunological and Biological Characterization of Excretor Factor from romastigotes”. Experimental Parasitology 47: 254, 1979.
5. El-On, J., Bradley, D.J. y Freeman J.: “Leishmania donovani: Action of Excretor Factor on Hydrolite. Enzyme Activitc of Macrophages from mice with Genetically Different Resistence to Infection” Experimental Parasitology. 49: 167, 1979.
6. Liew, F.Y., Hate, C. y Howard, J.: “Inmunologic Regulation of Experimental. Cutaneous Leishmaniasis. Y. Characterization of Effects and Specific Supressor T Cells”. The Journal oflnmunology 128: 1917,1982.
7. Reiner, N., Winnienc y McMaster R.: “Parasite Accesoty Cell Interactions in nurine Leishmaniasis”. The Journal of Inmunology 138: 1926, 1987.
8. Scott, P.A. y Farrell J.: “Experimental Leishmaniasis Inespecific Inmunodepression BALB/c nice Infected with Leishmaniasis Trojiica”. The J ournal of Inmunology 127: 2395, 1981.
9. Lowry O.M. J.; Roseborouhg, A.L.; Farry Randall R.J.: Protein meassurcment witli the folliw phenol reagent”. J. Biol. Chem. 193:265, 1951.
10. Dubois, M.K.; Gilíes, K.A.; Hamilton, J.K.; Bebers P.A.; y Smith F.: “Colorimetric Method for determination of sugars and related substances anal”. Chem. 28:350, 1956.
11. Mitchell, G.F. y Handman, E.; “T-linphocyte recognice Leishmania Glicoconjugates” . Parasitology Today, 1:63, 1985.
12. Londner, M.V.; Frankenburg, S.; Slutzky, G.M. y Grcemblatt, C.: “ Action of Leishmania Excretor Factor on human linphocyte, blast transformation”. Parsitic. Inmunology 5:249, 1983.
13. Mitchell, G.F. y Handman, E.; “The glycoconjugate derived from a Leishmania major receptor for macrophages is a suppressogenie, disease promoting antigen in murine cutaneus leishmaniosis”. Parasite Inmunology 8:255, 1986.
14. Liew, F.Y.: “Functional heterogeneity of CD4+ Tells in Leishmaniasis”. Inmunology Today. 10:40. 1989.
2. Schnur, L.F.: A. Zurkerman y Greenblatt, C.L.: “Leishmaniaí serotypes as distinguished by the gel diffusion of factors excreted in vitro and in vivo, lsr” . J.Med. Sci. 8:132, 1972.
3. Swtzky, G.M. y Greenblatt, C.L.: “Isolation of a Carbohidrate-Rich Inmunologically Active Factor from Cultures of Leishmania Trópica” Febs. Lett. 80:401, 1977.
4. El.-On, J., Schnur, L. y Greenblatt, C.L.: “Leishmania donovani: Physicochemical Inmunological and Biological Characterization of Excretor Factor from romastigotes”. Experimental Parasitology 47: 254, 1979.
5. El-On, J., Bradley, D.J. y Freeman J.: “Leishmania donovani: Action of Excretor Factor on Hydrolite. Enzyme Activitc of Macrophages from mice with Genetically Different Resistence to Infection” Experimental Parasitology. 49: 167, 1979.
6. Liew, F.Y., Hate, C. y Howard, J.: “Inmunologic Regulation of Experimental. Cutaneous Leishmaniasis. Y. Characterization of Effects and Specific Supressor T Cells”. The Journal oflnmunology 128: 1917,1982.
7. Reiner, N., Winnienc y McMaster R.: “Parasite Accesoty Cell Interactions in nurine Leishmaniasis”. The Journal of Inmunology 138: 1926, 1987.
8. Scott, P.A. y Farrell J.: “Experimental Leishmaniasis Inespecific Inmunodepression BALB/c nice Infected with Leishmaniasis Trojiica”. The J ournal of Inmunology 127: 2395, 1981.
9. Lowry O.M. J.; Roseborouhg, A.L.; Farry Randall R.J.: Protein meassurcment witli the folliw phenol reagent”. J. Biol. Chem. 193:265, 1951.
10. Dubois, M.K.; Gilíes, K.A.; Hamilton, J.K.; Bebers P.A.; y Smith F.: “Colorimetric Method for determination of sugars and related substances anal”. Chem. 28:350, 1956.
11. Mitchell, G.F. y Handman, E.; “T-linphocyte recognice Leishmania Glicoconjugates” . Parasitology Today, 1:63, 1985.
12. Londner, M.V.; Frankenburg, S.; Slutzky, G.M. y Grcemblatt, C.: “ Action of Leishmania Excretor Factor on human linphocyte, blast transformation”. Parsitic. Inmunology 5:249, 1983.
13. Mitchell, G.F. y Handman, E.; “The glycoconjugate derived from a Leishmania major receptor for macrophages is a suppressogenie, disease promoting antigen in murine cutaneus leishmaniosis”. Parasite Inmunology 8:255, 1986.
14. Liew, F.Y.: “Functional heterogeneity of CD4+ Tells in Leishmaniasis”. Inmunology Today. 10:40. 1989.
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Published
2017-06-16
How to Cite
1.
Armijos Moreta R, Armijos MV, Aguilar Torrentera F, Monroy A. Cinética de la Infección con Leishmania Mexicana en Ratones Balb/c y C57BL/6 previamente Inmunizados con Factor Excretor. Rev Fac Cien Med (Quito) [Internet]. 2017 Jun. 16 [cited 2024 Dec. 19];14(1-4):9-12. Available from: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/660
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ARTÍCULOS ORIGINALES
