Hyponatremia and traumatic brain injury, an important association. Case report

Authors

  • Jeremy Flores-Mora Hospital General del Sur de Quito, IESS, Quito, Ecuador
  • Miguel Jacob Ochoa-Andrade Universidad Central del Ecuador
  • Mikaela Jurado-Juna Hospital General del Sur de Quito, IESS, Quito, Ecuador
  • Renata Segovia-Laura Hospital General del Sur de Quito, IESS, Quito, Ecuador
  • Joseph Guerrero-González Hospital General del Sur de Quito, IESS, Quito, Ecuador

DOI:

https://doi.org/10.29166/rfcmq.v49i2.6682

Keywords:

hyponatremia, brain injuries, traumatic, clinical diagnosis, case report

Abstract

Introduction: Hyponatremia is found to be associated with approximately 10% of patients with traumatic brain injury. Despite its low frequency, the clinical intuition regarding this relationship underscores its significance in this case report.

Objective: Describe the association between hyponatremia and traumatic brain injury, aiming to enhance healthcare professionals' understanding of this correlation and to advocate for the implementation of more effective diagnostic and management strategies based on updated biochemical and anatomical predictions.

Case Presentation: A young adult male patient with a history of two traumatic brain injuries, severe serum hyponatremia, and persistent symptoms of dizziness and headache, treated with loop diuretics and oral sodium chloride, exhibited improvement after twenty days of hospitalization.

Discussion: Certain neurological alterations with evident clinical manifestation are characterized by low levels of serum sodium, possibly stemming from distinct anatomical and physiological causes. A causal relationship with a poorly described pathophysiological mechanism between hyponatremia and traumatic brain injury has been suggested.

Conclusion: Meticulous monitoring is imperative for patients with severe hyponatremia, even when clinical symptoms are minimal, as observed in this case. Furthermore, emphasis is placed on the need to investigate metabolic pathways that may be affected by traumatic brain injuries, potentially exerting a direct impact on blood sodium levels.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

References

Mejía-Sandoval HJ, Castellanos-Bueno R, Rangel-Rivera DA, Rangel-Rivera KL. Aspectos prácticos para la clasificación, diagnóstico y manejo de hiponatremia en el paciente hospitalizado. Rev Médicas UIS [Internet]. 2020[ Cited Apr 30, 2024];33(2):85–93. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-03192020000200010

Adrogué H, Madias N. Diagnosis and treatment of hyponatremia. American journal of kidney diseases: the official journal of the National Kidney Foundation [Internet]. 2014[ Cited Apr 30, 2024];64(5), 681–684. Available from: https://doi.org/10.1053/j.ajkd.2014.06.001

Parrales H. Hiponatremia: Diagnóstico y Tratamiento. [Internet]. 2022. [Cited May 6, 2024]. Available from: https://www.researchgate.net/publication/363266489

Esquinas NM, et al. Traumatismo craneoencefálico e hiponatremia, una asociación a tener en cuenta. Semergen [Internet]. 2017[ Cited Apr 30, 2024]. Available from: http://dx.doi.org/10.1016/j.semerg.2016.11.003

Las Heras J, Taboada M. Hiponatremia secundaria a diuréticos. Medifam [Internet]. 2001[ Cited Apr 30, 2024];11: 302-306. Available from: https://scielo.isciii.es/pdf/medif/v11n5/notaclinica4.pdf

Merino J, Villanueva R, Moyano M. Un paciente con hiponatremia. Med Integr [Internet]. 2000 [Cited May 15,2024];36(5):166–72. Available from: https://www.elsevier.es/es-revista-medicina-integral-63-articulo-un-paciente-con-hiponatremia-10022222

Chua TH, Ly M, Thillainadesan S, Wynne K. From renal salt wasting to SIADH. BMJ Case Rep [Internet]. 2018[ Cited Apr 30, 2024]. Available from: http://dx.doi.org/10.1136/bcr-2017-223606

Ternero J. Proyecto Hiponat: estudio multicéntrico prospectivo observacional sobre las características de la hiponatremia y su manejo en áreas de medicina interna. Tesis Doctoral. Universidad de Sevilla [Internet]. 2023[Cited May 12, 2024]. Available from: https://idus.us.es/handle/11441/143935

Richard H, Michael E, Jhon P. Treatment of hyponatremia: Syndrome of inappropriate antidiuretic hormone secretion (SIADH) and reset osmostat. Wolter Kluwer/UpToDate [Internet]. 2022[Cited May 12, 2024]. Available from: https://www.uptodate.com/contents/treatment-of-hyponatremia-syndrome-of-inappropriate-antidiuretic-hormone-secretion-siadh-and-reset-osmostat

Momi J, Tang C, Abcar A, Kujubu D, Sim J. Hyponatremia-what is cerebral salt wasting? The Permanente journal [Internet]. 2010[ Cited Apr 30, 2024];14(2), 62–65. Available from: https://doi.org/10.7812/TPP/08-066

Mellado-Orellana R, Sánchez-Herrera D, Deschamps-Corona A, et al. Hiponatremia para principiantes. Med Int Mex [Internet]. 2022 [Cited May 12, 2024]; 38(2):397-408. Available from: https://www.medigraphic.com/cgi-bin/new/resumen.cgi?IDARTICULO=104967

Barajas DE, Ruiz-Sánchez JG, Fernández A, Runkle de la Vega I, Ferrer JC, Ropero-Luis G, et al. Documento de consenso sobre el manejo de la hiponatremia del Grupo Acqua de la Sociedad Española de Endocrinología y Nutrición. Endocrinol Diabetes Nutr [Internet]. 2023 [Cited May 12, 2024]; 70:7–26. Available from: http://dx.doi.org/10.1016/j.endinu.2022.01.004

Mejía-Sandoval Harvey Julián, Castellanos-Bueno Rafael, Rangel-Rivera Diego Alejandro, Rangel-Rivera Karen Lorena. Aspectos prácticos para la clasificación, diagnóstico y manejo de hiponatremia en el paciente hospitalizado. Medicas UIS [Internet]. 2020. [Cited May 12, 2024]; 33(2): 85-93. Available from: http://www.scielo.org.co/scielo.php?script=sci_arttext&pid=S0121-03192020000200010&lng=en.

Gomes M, Matos AC. Abordagem do Doente Com Hiponatremia. RPMI [Internet]. 2021 [Cited May 9,2024];28(4):378-8. Available from: https://revista.spmi.pt/index.php/rpmi/article/view/278

Vásquez J, Jiménez R, Padilla P, Gracia D, Delgado S. Hiponatremia en el paciente neurológico: un acercamiento a los principales diagnósticos, una revisión sistemática de la literatura. Scientific & Education Medical Journal [Internet]. 2021[Cited May 9, 2024]; 3: 116-124. Available from: https://www.medicaljournal.com.co/index.php/mj/article/download/60/114

Pretus S, Alonso I, Baños A, Mariscal M. Manejo práctico de la hiponatremia. Revista electrónica de AnestesiaR [Internet]. 2021[Cited May 9, 2024];13(3):2. Available from: https://dialnet.unirioja.es/servlet/articulo?codigo=7878791

Published

2024-05-27

How to Cite

1.
Flores-Mora J, Ochoa-Andrade MJ, Jurado-Juna M, Segovia-Laura R, Guerrero-González J. Hyponatremia and traumatic brain injury, an important association. Case report. Rev Fac Cien Med (Quito) [Internet]. 2024 May 27 [cited 2024 Nov. 23];49(2):59-64. Available from: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/6682

Most read articles by the same author(s)