Miocardiopatía dilatada y enfermedad de Chagas: reporte de un caso en Ecuador
Resumen
La enfermedad de Chagas o tripanosomiasis americana, causada por Trypanosoma cruzi, protozoario transmitido por insectos hematófagos de la familia Reduviidae, se encuentra ampliamente documentada en el Ecuador.
Durante la infección se presentan tres fases: aguda, con niveles de parasitemia que pueden ser elevados, lo que permite detectar el parásito por microscopía de luz; fase intermedia o indeterminada; y, fase crónica donde casi no hay parásitos circulantes y pueden aparecer patologías asociadas como cardiopatías y/o megavisceras
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1. Taibi A, Plumas-Marty B, Guevara-E A, Schöneck R, Pessoa H, Loyens M, et al. Trypanosoma cruzi: immunity induced in mice and rats by trypomastigote excretory-secretory antigens and identification of a peptide sequence containing a T-cell epitope with protective activity. J Immunol 1993; 151: 2676-89.
2. Guevara-E A, Taibi A, Mullot-Billaut O, Ouaissi A. A polymerase chain reaction-based detection of Trypanosoma cruzi useful for specific diagnosis of human Chagas’ disease. J Clin Microb 1996; 34 (2): 485-86.
3. Black CL, Ocaña-Mayorga S, Riner DK, Costales JA, Lascano MS, Arcos-Terán L, et al. Seroprevalence of Trypanosoma cruzi in rural Ecuador and clustering of
seropositivity within households. Am J Trop Med Hyg 2009; 31(6): 1035-40.
4. Guevara AG, Garzón E, Bowen C, Córdova X, Gómez E, Ouaissi A. High infection rates of Triatoma dimidiata are associated with low levels of Trypanosoma cruzi seroprevalence in Pedro Carbo, Ecuador: Use of a tc24 gene-based PCR approach. Parasite 2005; 12: 65 – 68.
5. Chico M, Sandoval C, Guevara AG, Calvopiña M, Cooper P, Reed S, Guderian RH. Chagas´disease in Ecuador: Evidence for disease transmission in an indigenous
population in the Amazon region. Mem Inst Oswaldo Cruz 1997; 92 (3): 317-20.
6. Guevara AG, Eras JW, Recalde M, Vinueza L, Cooper PJ, Ouaissi A, Guderian RH. Severe digestive pathology associated with chronic Chagas disease in Ecuador:
report of two cases. Rev Soc Bras Med Trop 1997; 30:389-92.
7. Kawabata M , Uchiyama T, Mimori T, Hashiguchi Y, De Coronel VV. Association of electrocardiographic abnormalities with seropositivity to Trypanosoma cruzi in
Ecuador. Trans R Soc Trop Med Hyg 1987; 81:7-10.
8. Guevara AG, Ruiz JC, Houghton RL, Reynolds L, Sleath P, Benson D, Ouaissi A, Guderian RH. Evaluation of a recombinant protein (RTC24) and synthetic peptides
in anti-Trypanosoma cruzi positive samples from blood bank donors in chagasic endemic areas of Ecuador. Japan J Trop Med Hyg 1999; 27: 19-22.
2. Guevara-E A, Taibi A, Mullot-Billaut O, Ouaissi A. A polymerase chain reaction-based detection of Trypanosoma cruzi useful for specific diagnosis of human Chagas’ disease. J Clin Microb 1996; 34 (2): 485-86.
3. Black CL, Ocaña-Mayorga S, Riner DK, Costales JA, Lascano MS, Arcos-Terán L, et al. Seroprevalence of Trypanosoma cruzi in rural Ecuador and clustering of
seropositivity within households. Am J Trop Med Hyg 2009; 31(6): 1035-40.
4. Guevara AG, Garzón E, Bowen C, Córdova X, Gómez E, Ouaissi A. High infection rates of Triatoma dimidiata are associated with low levels of Trypanosoma cruzi seroprevalence in Pedro Carbo, Ecuador: Use of a tc24 gene-based PCR approach. Parasite 2005; 12: 65 – 68.
5. Chico M, Sandoval C, Guevara AG, Calvopiña M, Cooper P, Reed S, Guderian RH. Chagas´disease in Ecuador: Evidence for disease transmission in an indigenous
population in the Amazon region. Mem Inst Oswaldo Cruz 1997; 92 (3): 317-20.
6. Guevara AG, Eras JW, Recalde M, Vinueza L, Cooper PJ, Ouaissi A, Guderian RH. Severe digestive pathology associated with chronic Chagas disease in Ecuador:
report of two cases. Rev Soc Bras Med Trop 1997; 30:389-92.
7. Kawabata M , Uchiyama T, Mimori T, Hashiguchi Y, De Coronel VV. Association of electrocardiographic abnormalities with seropositivity to Trypanosoma cruzi in
Ecuador. Trans R Soc Trop Med Hyg 1987; 81:7-10.
8. Guevara AG, Ruiz JC, Houghton RL, Reynolds L, Sleath P, Benson D, Ouaissi A, Guderian RH. Evaluation of a recombinant protein (RTC24) and synthetic peptides
in anti-Trypanosoma cruzi positive samples from blood bank donors in chagasic endemic areas of Ecuador. Japan J Trop Med Hyg 1999; 27: 19-22.
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Publicado
2017-05-29
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1.
Guevara-Espinoza Ángel, Cisneros-Espín F, Runruil-Mora G, Calvopiña-Hinojosa M, Vicuña-Almeida Y, Perugachi-Cevallos C. Miocardiopatía dilatada y enfermedad de Chagas: reporte de un caso en Ecuador. Rev Fac Cien Med (Quito) [Internet]. 29 de mayo de 2017 [citado 19 de diciembre de 2024];38(1-2):92-3. Disponible en: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/1123
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