Utilidad de amilasa y lipasa en diagnóstico y tratamiento de dolor abdominal agudo

Abstract

The objective of the research was to evaluate how useful is the amylase and serum lipase in the diagnosis and control
of treatment of patients with acute abdominal pancreatic and non-pancreatic pain who attended at NORTHOSPITAL
Hospital in Quito during the period October to December 2015 and had elevated serum amylase and lipase
serum. The variables: age, gender, pathological and family history, reason for consultation, signs and symptoms,
laboratory and imaging testing, diagnosis and treatment were obtained from medical records. Tools like: median,
frequency, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), ROC curves, t-test
for related and ANOVA samples of a factor were employed in the statistical part of this study. It was evidenced,
using required statistical tests, that serum lipase has a higher sensitivity (90.91%) compared to amylase (63.3%
sensitivity) for pancreatitis diagnosis. Both biochemical parameters offer a 100% specificity. Serum amylase and
lipase are elevated in acute pancreatitis and in other non-pancreatic pathologies; therefore other lab and imaging
test are needed in order to achieve an effective diagnosis.