Suplementarion dietetica con calcio en la Hipertension inducida por el embarazo
Abstract
La hipertensión inducida por el embarazo constituye la, primera causa de morbi—mortalidad materna en Ecuador. Su etiopatogenia continúa siendo controvertida, a pesar de que se ha demostrado de que se trata de un estado de deficiencia de prostaciclina. Observaciones epidemiológicas han llévado a proponer una relación entre ingesta de calcio e incidencia de la enfermedad. Nosotros hemos estudiado esta aparente relación inversa y hemos demostrado que la súpleme litación con calcio disminuye significativamente la incidencia de la enfermedad. Resultados experimentales nos han llevado a proponer que esta acción de la suplementación con calcio podría estar mediada por estimulación de la síntesis vascular de prostaciclina. . (Revista de la Facultad de Ciencias Médicas (Quito), 12: 34,,1987).
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References
1. López—Llera, M.: La toxemia del Embarazo. Ciudad de México: Editoriál Limusa, 2rid. ed., 1985.
2. Long, P.A., Abcll, D.A., and Beisher, N.A.: Fetal growt retardation and pre—eclampsia. Br. J. Obstet Gynecol., 87:13,1980.
3. Jijón, A.: Actualización del tratamiento de la preeclampsia y eclampsia. Educación Médica Continuada, 12: 25,1985.
4. McCarron, D.A., and Morris, C.D.: Calciurn,paratyroid hormone, and hypertensión. In: Year Book Medical Publishers, Inc. 1984. .
5. Me Carrón, D. A., Morris, C.D., and Colé, G.: Dietary calciurn in human hypertensión. Science, 217:267,1982.
6. McCarron, D.A., Morris, C.D. Henry, H.J., et al.: Blood pressure nutrient intake in the United States. Science, 224:1392,1984.
7. Masironi, R., Koirtyohann, S.A., Pier'se, J.O., and Schamachula, R.A.: Calciurn content of river water, trace element concentratiorí in toenails, and blood pressure in village populátions iri New Guiriea. Sci Total Environ 6 : 41:1976.
8. Belizan, J.M. and Villar, J.: The relationship betwocn calcium intake and edema—proteinuria—hypertension—gestosis: an hypothesis. Am. J. Clin. Nut. 33: 2202,1980.
9.‘ Villar, J., Belizan, J. M., and Fischer, P.J.: Epidemiologic óbservations on the relationship between calcium intake and eclampsia. Int. J. Gynecol. Obstet. 21: 271,1983.
10. Grobbsem, D.E., and Hoffman, A.: Effect of calcium supplementarion ondiastolic blood pressure in young peo pie with mild hypertension. Lancet i:703,1986.
11. McCarron, D.A., and Morris, C.D.: Blood pressure respons tó oral calcium in persons with mild t'ó moderate hypertension. Ann, Int. Med. 103: 825,1985.
12. Tabuchi, Y., Ogihara, Y., Hashizuma, K., el al,: Hypotensive effect of long—term oral calcium suplementátion in elderly patients with essential hypertension. J. Clin. Hypert. 3: 254,1986.
13. Belizan, J.M., Villar, J., Pineda, O, et al.: Blood pressure reduction in young adults with calcium suplementátion: a randómized clinical trial. JAMA. 249:1161,1983.
14. Belizan, J.M., Villar, J.,Salazar, A., et. al.; Preliminary evidence of the effect of calcium supplementation on blood pressure in normal pregnant women. Am. J. Obstet. Gyneco. 146:175,1983.
15. Food and Nutrition Bóard.: Recommended dietary allowances National Research Council. National Acádemy of Sciences, 1980.
16. Duggin, G.G., Lynehan, R.C., Dale, N.E., et al.: Calcium balance pregnancy. Lancet, ii: 499,1974.
17. Pitkin, R.M.: Calcium metabolism in pregnancy: A review. Am.J. Obstet Gyneco. 150:124, 1985.
18. Pitkin, R.M., and Gebhardt, M.P.: Serum calcium concentrations in human pregnancy. Am. J. Obstet. Gynecol. 127:775,1977.
19. Pitkin, R.M., Reynolds W.A., and Williams, G. A.: Calcium metabolism in normal pregnancy: A longitudinal stndy. Am. J. Obstet. Gyneco. 133:781,1979.
20. Pitkin, R.M., Crvjshank, D.P., Schaubergerm C. W., Reynolds, W.A., Williams^ GA. andHargis, G.K.: Hormonas calcitropicas fetales y homeostasis neonatal del calcio. Pediatrics (Ed. Esp.). 10:37.
21. Pitkin, R.M.: Calcium metabolism in pregnancy: A review. Am J. Obstet. gynecol. 121:724, 1975.
22. López—Jaranülló, P., Narváez, M., Alvarez, M., Yépez, R.: Niveis de calcio iónico sérico durante a gravidez normal e toxemia. Arq. Bras. Endocrinol. Metabol. 29:8,1985.
23. Cushard, W.G., Creditor, M.A., Canterbury, J.M., and Reiss, F.; Physiológy hyperparathyroidis in pregnancy. J. Clin. Endocrinol. Metabol 34:767,1972.
24. Reitz, R.E., Daane, T.A., Wood, J.R. and Weistein, R.L.: Calcium, Magnesium, phosforusand parathyroid hormone interrelationship in pregnancy and new borns infants. Obstet. Gynecol. 50:701,1977.
25. Tanaka, Y., Castillo, L. and DeLuca., H.F.: Control of renal Vitamin D hydroxilase in birds by sex hormones. Proc. Nati, Acad. Scú USA 73:2701,1976.
26. Spanos, E., Colston, K.W., Evans, I.M., et. al.: Effect on prolactin on Vitamin D metabolism. Molec. Cell Endocrinol. 5:163,1976.
27. López—Jaramillo, P., Narváez, M., Alvarez, M. y Yépez, R.: Toxemia del embarazo, calcio y prostaglandinas: Una revisión. Revista de la Facultad de Ciencias Médica (Quito) 9:39, 1984.
28. López—Jaramillo, P., Narváez, M. and Yépez, R.: Effect of calcium supplementations on the vascular sensitivity to angiotensin II in pregnant women. Am. J. Obstet. Gynecol. 156:261, 1987.
29. López—Jaramillo, P., Narváez, M., Alvarez, M., Gaibor, M., Moscoso, H, and Yépez, R.: Calcium supplementation reduces the risk of pregnancy induced hypertension. Am. J. Obstet. Gynecol. Submited. 1987.
30. Tan, C.M., Raman, A. and Sinnathyrarm T.A.: Serum ionic calcium levels during pregnancy. J. Obstet. Gynecol. Br. Commonwlth. 76: 694,1972.
34. Narváez, M., Yépez, R. y López—Jaramillo, P.: Prevención de la hipertensión indudda por el embarazo en gestantes de riesgo identificadas por “ roll over test” con suplementación dietética de calcio. Revista de la Facultad de Ciencias Médicas (Quito) 11: In press.
35. López—Jaramillo, P., Guarner, F. and Moneada, S.: Effects of calcium and parathyroid hormone on prostaeyelin synthesis by vascular tissue. Life Sci 40: 983,1987.
36. Makila, Ü,M. . Viinikka, L., Ylikorkala, O.: Evidencie that prostaeyelin deficiency is a specific feacture in pre—eclampsia. Am. J. Obstet. Gynecol. 148:772,1984.
37. Ayachi, S.: Increase in dietary calcium lowers blood pressure in the spontaneusly hypertensive rat. Metabolism 28:1234,1979.
2. Long, P.A., Abcll, D.A., and Beisher, N.A.: Fetal growt retardation and pre—eclampsia. Br. J. Obstet Gynecol., 87:13,1980.
3. Jijón, A.: Actualización del tratamiento de la preeclampsia y eclampsia. Educación Médica Continuada, 12: 25,1985.
4. McCarron, D.A., and Morris, C.D.: Calciurn,paratyroid hormone, and hypertensión. In: Year Book Medical Publishers, Inc. 1984. .
5. Me Carrón, D. A., Morris, C.D., and Colé, G.: Dietary calciurn in human hypertensión. Science, 217:267,1982.
6. McCarron, D.A., Morris, C.D. Henry, H.J., et al.: Blood pressure nutrient intake in the United States. Science, 224:1392,1984.
7. Masironi, R., Koirtyohann, S.A., Pier'se, J.O., and Schamachula, R.A.: Calciurn content of river water, trace element concentratiorí in toenails, and blood pressure in village populátions iri New Guiriea. Sci Total Environ 6 : 41:1976.
8. Belizan, J.M. and Villar, J.: The relationship betwocn calcium intake and edema—proteinuria—hypertension—gestosis: an hypothesis. Am. J. Clin. Nut. 33: 2202,1980.
9.‘ Villar, J., Belizan, J. M., and Fischer, P.J.: Epidemiologic óbservations on the relationship between calcium intake and eclampsia. Int. J. Gynecol. Obstet. 21: 271,1983.
10. Grobbsem, D.E., and Hoffman, A.: Effect of calcium supplementarion ondiastolic blood pressure in young peo pie with mild hypertension. Lancet i:703,1986.
11. McCarron, D.A., and Morris, C.D.: Blood pressure respons tó oral calcium in persons with mild t'ó moderate hypertension. Ann, Int. Med. 103: 825,1985.
12. Tabuchi, Y., Ogihara, Y., Hashizuma, K., el al,: Hypotensive effect of long—term oral calcium suplementátion in elderly patients with essential hypertension. J. Clin. Hypert. 3: 254,1986.
13. Belizan, J.M., Villar, J., Pineda, O, et al.: Blood pressure reduction in young adults with calcium suplementátion: a randómized clinical trial. JAMA. 249:1161,1983.
14. Belizan, J.M., Villar, J.,Salazar, A., et. al.; Preliminary evidence of the effect of calcium supplementation on blood pressure in normal pregnant women. Am. J. Obstet. Gyneco. 146:175,1983.
15. Food and Nutrition Bóard.: Recommended dietary allowances National Research Council. National Acádemy of Sciences, 1980.
16. Duggin, G.G., Lynehan, R.C., Dale, N.E., et al.: Calcium balance pregnancy. Lancet, ii: 499,1974.
17. Pitkin, R.M.: Calcium metabolism in pregnancy: A review. Am.J. Obstet Gyneco. 150:124, 1985.
18. Pitkin, R.M., and Gebhardt, M.P.: Serum calcium concentrations in human pregnancy. Am. J. Obstet. Gynecol. 127:775,1977.
19. Pitkin, R.M., Reynolds W.A., and Williams, G. A.: Calcium metabolism in normal pregnancy: A longitudinal stndy. Am. J. Obstet. Gyneco. 133:781,1979.
20. Pitkin, R.M., Crvjshank, D.P., Schaubergerm C. W., Reynolds, W.A., Williams^ GA. andHargis, G.K.: Hormonas calcitropicas fetales y homeostasis neonatal del calcio. Pediatrics (Ed. Esp.). 10:37.
21. Pitkin, R.M.: Calcium metabolism in pregnancy: A review. Am J. Obstet. gynecol. 121:724, 1975.
22. López—Jaranülló, P., Narváez, M., Alvarez, M., Yépez, R.: Niveis de calcio iónico sérico durante a gravidez normal e toxemia. Arq. Bras. Endocrinol. Metabol. 29:8,1985.
23. Cushard, W.G., Creditor, M.A., Canterbury, J.M., and Reiss, F.; Physiológy hyperparathyroidis in pregnancy. J. Clin. Endocrinol. Metabol 34:767,1972.
24. Reitz, R.E., Daane, T.A., Wood, J.R. and Weistein, R.L.: Calcium, Magnesium, phosforusand parathyroid hormone interrelationship in pregnancy and new borns infants. Obstet. Gynecol. 50:701,1977.
25. Tanaka, Y., Castillo, L. and DeLuca., H.F.: Control of renal Vitamin D hydroxilase in birds by sex hormones. Proc. Nati, Acad. Scú USA 73:2701,1976.
26. Spanos, E., Colston, K.W., Evans, I.M., et. al.: Effect on prolactin on Vitamin D metabolism. Molec. Cell Endocrinol. 5:163,1976.
27. López—Jaramillo, P., Narváez, M., Alvarez, M. y Yépez, R.: Toxemia del embarazo, calcio y prostaglandinas: Una revisión. Revista de la Facultad de Ciencias Médica (Quito) 9:39, 1984.
28. López—Jaramillo, P., Narváez, M. and Yépez, R.: Effect of calcium supplementations on the vascular sensitivity to angiotensin II in pregnant women. Am. J. Obstet. Gynecol. 156:261, 1987.
29. López—Jaramillo, P., Narváez, M., Alvarez, M., Gaibor, M., Moscoso, H, and Yépez, R.: Calcium supplementation reduces the risk of pregnancy induced hypertension. Am. J. Obstet. Gynecol. Submited. 1987.
30. Tan, C.M., Raman, A. and Sinnathyrarm T.A.: Serum ionic calcium levels during pregnancy. J. Obstet. Gynecol. Br. Commonwlth. 76: 694,1972.
34. Narváez, M., Yépez, R. y López—Jaramillo, P.: Prevención de la hipertensión indudda por el embarazo en gestantes de riesgo identificadas por “ roll over test” con suplementación dietética de calcio. Revista de la Facultad de Ciencias Médicas (Quito) 11: In press.
35. López—Jaramillo, P., Guarner, F. and Moneada, S.: Effects of calcium and parathyroid hormone on prostaeyelin synthesis by vascular tissue. Life Sci 40: 983,1987.
36. Makila, Ü,M. . Viinikka, L., Ylikorkala, O.: Evidencie that prostaeyelin deficiency is a specific feacture in pre—eclampsia. Am. J. Obstet. Gynecol. 148:772,1984.
37. Ayachi, S.: Increase in dietary calcium lowers blood pressure in the spontaneusly hypertensive rat. Metabolism 28:1234,1979.
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2017-06-16
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1.
Lopez P. Suplementarion dietetica con calcio en la Hipertension inducida por el embarazo. Rev Fac Cien Med (Quito) [Internet]. 2017 Jun. 16 [cited 2024 Dec. 19];12(1-2):34-9. Available from: https://revistadigital.uce.edu.ec/index.php/CIENCIAS_MEDICAS/article/view/601
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