Preterm Labor: nifedipine vs atosiban treatment. Bilbiographic theoretical review
DOI:
https://doi.org/10.29166/rfcmq.v47i2.3266Keywords:
obstetric labor premature, tocolysis, nifedipine, efficacyAbstract
Background: The threat of preterm birth is a global and national public health problem. Prematurity is linked to complications such as pulmonary immaturity and central nervous system lesions, which require timely treatment.
Objective: To perform an objective comparison of the results of the treatment of the threat of premature delivery, using nifedipine or atosiban, carrying out an updated theoretical review of the subject, to offer the scientific community a tool for research on a frequent subject of high maternal and fetal risk.
Materials y Methods: There was a bibliographic search in specialized databases. Articles published in high impact indexed journals in the last 5 years were included. The quality of the articles included was assessed, using the Sacket methodology, and the risk of bias, according to the Cochrane methodology.
Results: There was an agreement among the authors consulted there are no significant differences in the tocolytic effect of atosiban and nifedipine.
Conclusions: The academic literature seems to agree that the effectiveness of atosiban and nifedipine as tocolytic agents is similar, with both drugs prolonging pregnancy with the risk of preterm delivery, which is the fundamental purpose of tocolysis.
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