RELACIÓN DE LA ALFA AMILASA SALIVAL CON EL SUEÑO.

Autores/as

  • Jorge Orlando Ponce Universidad Nacional del Nordeste

Palabras clave:

Alfa-amilasa salival, sueño, ritmo circadiano

Resumen

La alfa-amilasa salival es una enzima regulada por el sistema nervioso simpático que refleja niveles de estrés y está asociada a la calidad del sueño. Objetivo: Analizar la relación entre los niveles de alfa-amilasa salival y la calidad del sueño, considerando su utilidad como biomarcador no invasivo. Metodología: Se realizó una revisión bibliográfica de la literatura mediante la metodología PRISMA, utilizando las bases de datos PubMed, Scopus y EBSCO Host para identificar estudios publicados entre 2019 y 2023. Resultados: Los niveles elevados de alfa-amilasa salival están relacionados con una activación simpática excesiva, que afecta negativamente la calidad del sueño, especialmente en situaciones de estrés, como la privación de sueño en estudiantes y profesionales de la salud. Además, intervenciones como la atención plena y las técnicas de relajación reducen los niveles de alfa-amilasa salival y mejoran la calidad del sueño. Conclusiones: Los hallazgos subrayan la relevancia de AAs como un biomarcador no invasivo del sueño y el estrés, útil para explorar su papel en la regulación del equilibrio fisiológico.

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Citas

-Oppenheim FG, Salih E, Siqueira WL, Zhang W, Helmerhorst EJ. Salivary proteome and its genetic polymorphisms. Annals of the New York Academy of Sciences. 2007; 1098:22–50. doi: 10.1196/annals.1384.030

-3-Nater UM, Rohleder N, Schlotz W, Ehlert U, Kirschbaum C. Determinants of the diurnal course of salivary alpha-amylase. Psychoneuroendocrinology. 2007;32:392–401. doi: 10.1016/j.psyneuen.2007.02.007.

-Strahler J, Skoluda N, Kappert MB, Nater UM. Simultaneous measurement of salivary cortisol and alpha-amylase: Application and recommendations. Neurosci Biobehav Rev. 2017 Dec; 83:657-677. doi: 10.1016/j.neubiorev.2017.08.015.

-Gehrman PR, Hall M, Barilla H, Buysse D, Perlis M, Gooneratne N, Ross RJ. Stress Reactivity in Insomnia. Behav Sleep Med. 2016;14(1):23-33. doi: 10.1080/15402002.2014.940112.

-Klaus K, Doerr JM, Strahler J, Skoluda N, Linnemann A, Nater UM. Poor night's sleep predicts following day's salivary alpha-amylase under high but not low stress. Psychoneuroendocrinology. 2019 Mar; 101:80-86. doi: 10.1016/j.psyneuen.2018.10.030

-Suh M. The association of salivary alpha-amylase, heart rate variability, and psychological stress on objectively measured sleep behaviors among college students. Frontiers of Nursing. 2022;9(1): 63-70. https://doi.org/10.2478/fon-2022-0008.

-Hall SJ, Aisbett B, Robertson SJ, Ferguson SA, Turner AI. Salivary alpha amylase in on-call from home fire and emergency service personnel. Endocr Connect. 2017 Nov;6(8):637-646. doi:10.1530/EC-17-0192.

-Wei Q, Ta G, He W, Wang W, Wu Q. Stilbene Glucoside, a Putative Sleep Promoting Constituent from Polygonum multiflorum Affects Sleep Homeostasis by Affecting the Activities of Lactate Dehydrogenase and Salivary Alpha Amylase. Chem Pharm Bull (Tokyo). 2017;65(11):1011-1019. doi: 10.1248/cpb.c17-00275.

- Ali N, Nater UM. Salivary Alpha-Amylase as a Biomarker of Stress in Behavioral Medicine. Int J Behav Med. 2020 Jun;27(3):337-342. doi: 10.1007/s12529-019-09843-x.

-Van Lenten SA, Doane LD. Examining multiple sleep behaviors and diurnal salivary cortisol and alpha-amylase: Within- and between-person associations. Psychoneuroendocrinology. 2016 Jun; 68:100-10. doi: 10.1016/j.psyneuen.2016.02.017.

-Segal SK. Neuroscience meets salivary bioscience: An integrative perspective. Behav Neurosci. 2016 Apr;130(2):156-75. doi: 10.1037/bne0000141.

-MJ, McKenzie JE, Bossuyt PM, et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021;372: n71.

-Pajcin M, White JM, Banks S, Dorrian J, Paech GM, Grant CL, Johnson K, Tooley K, Aidman E, Fidock J, Kamimori GH, Della Vedova CB. Effects of strategic early-morning caffeine gum administration on association between salivary alpha-amylase and neurobehavioural performance during 50 h of sleep deprivation. Accid Anal Prev. 2019 May; 126:160-172. doi: 10.1016/j.aap.2018.01.026.

-Kusmawan D, Eka Rini W, Aurora W. Relation of Salivary Alpha-Amylase (sAA) Concentration to Fatigue Biomarkers in Palm Oil Office Workers in Jambi Province: Preliminary Study. *2023. Makara Journal of Science: Vol. 27: Iss. 4, Article 5. DOI: 10.7454/mss.v27i4.1450

-28. Shen JL, Hung BL, Fang SH. Horticulture therapy affected the mental status, sleep quality, and salivary markers of mucosal immunity in an elderly population. Sci Rep. 2022 Jun 17;12(1):10246. doi: 10.1038/s41598-022-14534-x.

-Semaan, R et al. “Does workplace telepressure get under the skin? Protocol for an ambulatory assessment study on wellbeing and health-related physiological, experiential, and behavioral concomitants of workplace telepressure.” BMC psychology vol. 11,1 145. 3 May. 2023, doi:10.1186/s40359-023-01123-4

-25. Vivarelli, S et al. “Salivary Biomarkers Analysis and Neurobehavioral Assessment in Nurses Working Rotation Shifts: A Pilot Study.” International journal of environmental research and public health vol. 20,7 5376. 3 Apr. 2023, doi:10.3390/ijerph20075376

-Chen M, Sun J, Chen TZ, Xu DZ, Wan J, Wang Q, Li YG. Loss of nocturnal dipping pattern of skin sympathetic nerve activity during and following an extended-duration work shift in residents in training. J Cardiol. 2021 Dec;78(6):509-516. doi: 10.1016/j.jjcc.2021.06.006.

-Pérez-Valdecantos D, Caballero-García A, Bello HJ, Noriega-González D, Palomar-Ciria N, Roche A, Roche E, Córdova-Martínez A. Professional Quality of Life of Healthcare Workers in Hospital Emergency Departments. Behav Sci (Basel). 2022 Jun 13;12(6):188. doi: 10.3390/bs12060188.10.1016/j.psyneuen.2022.105873.

- Krempel R, Schleicher D, Jarvers I, Ecker A, Brunner R, Kandsperger S. Sleep quality and neurohormonal and psychophysiological accompanying factors in adolescents with depressive disorders: study protocol. BJPsych Open. 2022 Mar 3;8(2):e57. doi: 10.1192/bjo.2022.29.

-Thieux M, Guyon A, Herbillon V, Merle L, Lachaux JP, Plancoulaine S, Seugnet L, Franco P. Interest of the BLAST paradigm and salivary markers for the evaluation of sleepiness in drivers. Front Neurosci. 2022 Sep 7; 16:991528. doi: 10.3389/fnins.2022.991528.

-Rebolledo Meza LF, Galvan Esparza JD, Fernandez Delgado JCM, Lule Espinosa G, Villanueva Tapia LA, Aguilar Zavala H. Marcadores de estrés, calidad de sueño, ansiedad y estrés percibido en estudiantes universitarios. JC [Internet]. 9 de septiembre de 2022 [citado 4 de diciembre de 2024];16:1-8. Disponible en: https://www.jovenesenlaciencia.ugto.mx/index.php/jovenesenlaciencia/article/view/3614

-Suardiaz-Muro M, Morante-Ruiz M, Ortega-Moreno M, Ruiz MA, Martín-Plasencia P, Vela-Bueno A. Sueño y rendimiento académico en estudiantes universitarios: revisión sistemática [Sleep and academic performance in university students: a systematic review]. Rev Neurol. 2020 Jul 16;71(2):43-53. Spanish. doi: 10.33588/rn.7102.2020015.

-Reffi AN, Cheng P, Kalmbach DA, Jovanovic T, Norrholm SD, Roth T, Drake CL. Is a blunted cortisol response to stress a premorbid risk for insomnia? Psychoneuroendocrinology. 2022 Oct; 144:105873. doi: 10.1016/j.psyneuen.2022.105873.

- Kurdi MS, Ramaswamy AH, Kumar LA, Choukimath SM, Jangi AA. Use of a non-invasive biomarker salivary alpha-amylase to assess the role of probiotics in sleep regulation and stress attenuation in surgical patients: A randomised double-blind clinical trial. Indian J Anaesth. 2021 May;65(5):390-397. doi: 10.4103/ija.IJA_1498_20.

-Lopresti AL, Smith SJ, Ali S, Metse AP, Kalns J, Drummond PD. Effects of a Bacopa monnieri extract (Bacognize®) on stress, fatigue, quality of life and sleep in adults with self-reported poor sleep: A randomised, double-blind, placebo-controlled study. J Funct Foods. 2021 Oct;85: 104671. doi: 10.1016/j.jff.2021.104671.

-Tu PC, Cheng WC, Hou PC, Chang YS. Effects of types of horticultural activity on the physical and mental state of older individuals. Int J Environ Res Public Health. (2020) 17:5225. doi: 10.3390/ijerph17145225

-Foldes ST, Jensen AR, Jacobson A, Vassall S, Foldes E, Guthery A, Brown D, Levine T, Tyler WJ, Frye RE. Transdermal Electrical Neuromodulation for Anxiety and Sleep Problems in High-Functioning Autism Spectrum Disorder: Feasibility and Preliminary Findings. J Pers Med. 2021 Dec 6;11(12):1307. doi: 10.3390/jpm11121307.

Publicado

2025-03-04

Cómo citar

Ponce, J. O. (2025). RELACIÓN DE LA ALFA AMILASA SALIVAL CON EL SUEÑO. Odontología, 27(Especial). Recuperado a partir de https://revistadigital.uce.edu.ec/index.php/odontologia/article/view/7828

Número

Sección

Revisión de Literatura