Periodontal conditions associated with hiposalivation in patients with Down syndrome
DOI:
https://doi.org/10.29166/odontologia.vol20.n1.2018-75-87Keywords:
Periodontics, Down Syndrome, XerostomiaAbstract
The periodontal diseases course in Down syndrome (DS) are earlier and aggressive and are mediated by numerous factors, such as oral hygiene habits, inflammatory profile and salivary alterations. Objective: To evaluate how the hyposalivation and other salivary parameters can influence a periodontal disease on patients with Down syndrome in different ages. Material and methods: A sample composed by 124 patients (Group A – 62 Down syndromes; Group B – 62 Non-syndromic patient) from 6 to 52 years old was excessed to evaluate the salivary parameters (salivary flow, pH and buffer capability) and periodontal diseases (plaque index, bleeding probing, probing depth and others). Also, was collected information about general health and oral hygiene habits. Results: The Group A exhibited high rate of plaque, low buffer capacity and low salivary flow. It was found a high prevalence of periodontal diseases in DS patients and a correlation among the low salivary flow and the severity of the periodontal disease (correlation = -0,27, p = 0,002). These data reveal the impact upon the salivary indicator and the periodontal disease. Conclusion: Patients with DS and hyposalivation present a greater risk to developing periodontal disease.
Downloads
References
chwertner C, Moreira MJ, Faccini LS, Hashizume LN. Biochemical composition of the saliva and dental biofilm of children with Down syndrome. Int J Paediatr Dent. 2016;26(2):134-40.
Lopez-Perez R, Borges-Yanez SA, Jimenez-Garcia G, Maupome G. Oral hygiene, gingivitis and periodontitis in persons with Down syndrome. Special Care Dentistry. 2002;22:214-20.
Desai SS. Down Syndrome: a review of literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84(3):279-85.
Moraes LME, Moraes LC, Dotto NG, Dotto PP, Santos RNA. Dental anomalies in patients with down syndrome. Braz. Dent. Journal. 2007; (8)4:123-5.
Souza RC, Giovani EM. Indicadores salivares e o risco de cárie na Síndrome de Down utilizando o software Cariogram®. Rev. Bras. Odontol. 2016 Mar; 73(1): 47-54.
Linossier A, Valenzuela CY, Toledo H. Differences of the oral colonization by Streptococcus of the mutans group in children and adolescents with Down syndrome, mental retardation and normal controls. Med Oral Patol Oral Cir Bucal. 2008;13(9):E536-9.
Shapira J, Stabholz A, Schurr D, Sela M, Mann J. Carie levels, Streptococcus mutans counts, salivary pH, and periodontal treatment needs of adult Down syndrome patients. Spec Care Dentist. 1991;11(6):248-51.
de Sousa MC, Vieira RB, Dos Santos DS, Carvalho CA, Camargo SE, Mancini MN, de Oliveira LD. Antioxidants and biomarkers of oxidative damage in the saliva of patients with Down’s syndrome. Arch Oral Biol. 2015 Apr;60(4):600-5.
Ferreira R, Michel RC, Greghi SL, Resende ML, Sant’Ana AC, Damante CA, Zangrando MS. Prevention and Periodontal Treatment in Down Syndrome Patients: A Systematic Review. PLoS One. 2016 Jun 29;11(6):e0158339.
Chaushu S, Becker A, Chaushu G, Shapira J. Stimulated parotid salivary flow rate in patients with Down syndrome. Spec Care Dentist. 2002a;22(1):41-4.
Areias C, Sampaio-Maia B, Pereira Mde L, Azevedo A, Melo P, Andrade C, et al. Reduced salivary flow and colonization by mutans streptococci in children with Down syndrome. Clinics (São Paulo). 2012;67(9):1007-11.
Jara L, Ondarza A, Blanco R, Rivera L. Composition of the parotid saliva in Chilean children with Down’s syndrome. Arch Biol Med Exp. 1991;24(1):57-60.
Siqueira WLOE, Mustacchi Z, Nicolau J. Electrolyte concentrantions in saliva of children age 6-10 years with Down syndrome. Oral Surg Oral Med Oral Pathol Oral Radio Endod. 2004,98:76-9.
Yarat A, Akyuz S, Koc L, Erdem H, Emekli N. Salivary sialic acid, protein, salivary flow rate, pH, buffering capacity and caries indices in subjects with Down’s syndrome. J Dent. 1999;27(2):115-8.
Khocht A, Yaskell T, Janal M, Turner BF, Rams TE, Haffajee AD, Socransky SS. Subgingival microbiota in adult Down syndrome periodontitis. J Periodontal Res. 2012 Aug;47(4):500-7.
Faria Carrada C, Almeida Ribeiro Scalioni F, Evangelista Cesar D, Lopes Devito K, Ribeiro LC, Almeida Ribeiro R. Salivary Periodontopathic Bacteria in Children and Adolescents with Down Syndrome. PLoS One. 2016 Oct 11;11(10):e0162988.
Cavalcante LB, Pires JR, Scarel-Caminaga RM. Doença periodontal em indivíduos com Síndrome de Down: enfoque genético. RGO 2009;57(4).
Amano A, Kishima T, Arikama S, Nakagawa J, Hamada S, Morisaki I. Relationship of periodontopathic bacteria with early-onset periodontitis in Down syndrome. J Periodontol 2001; 72(3): 368–73.
Cichon P, Crawford L, Grima WD. Early-onset periodontitis associated with Down’s syndrome--clinical interventional study. Ann Periodontol. 1998;3(1):370-80.
Moreira MJ, Schwertner C, Grando D, Faccini LS, Hashizume LN. Oral Health Status and Salivary Levels of Mutans Streptococci in Children with Down Syndrome. Pediatr Dent. 2015 Jul-Aug;37(4):355-60.