Evaluation of branched-chain amino acid supplementation on productive performance and biochemical variables in weaned piglets

Main Article Content

Jorge Luis Paillacho Cabrera
José Manuel More Montoya
Eduardo Fabián Aragón Vásquez
Renán Patricio Mena Pérez
Jimmy Rolando Quisirumbay Gaibor

Abstract

Weaning in mammals is an event of maximum stress that generates metabolic wear with mobilization of nutrients for the maintenance of body homeostasis. Piglets experience decreased feed intake and lower productive performance. The objective of the present study was to evaluate the effect of dietary supplementation of branched-chain amino acids (BCAA) in weaned piglets by measuring productive performance and biochemical blood tests. A total of 16 piglets distributed in four treatments were used: T1 = control 1 (without milk supplement), T2 = control 2 (milk supplement), T3 = milk supplement + BCAA (0.5% form milk supplement composition), T4 = milk supplement + BCAA (1%). The piglets of the four groups presented a similar productive performance in all the variables analyzed: daily weight gain, feed consumption and feed conversion. Regarding blood variables, no statistical difference was found either. BCAA supplementation through feed did not improve productive performance or biochemical variables in piglets weaned at 28 days after 7 days of administration.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Article Details

How to Cite
Paillacho Cabrera, J. L., More Montoya, J. M., Aragón Vásquez, E. F., Mena Pérez, R. P., & Quisirumbay Gaibor, J. R. (2022). Evaluation of branched-chain amino acid supplementation on productive performance and biochemical variables in weaned piglets. Siembra, 9(2), e3991. https://doi.org/10.29166/siembra.v9i2.3991
Section
Original article
Author Biographies

Jorge Luis Paillacho Cabrera, Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia. Jerónimo Leiton y Gato Sobral. 170129. Quito, Ecuador

https://orcid.org/0000-0003-3263-991X

José Manuel More Montoya, Universidad Nacional de San Antonio Abad del Cusco. Escuela Profesional de Ingeniería Agropecuaria Filial Santo Tomás, Facultad de Ciencias Agrarias. Av. de la Cultura, Nro. 733. 080101. Cusco, Perú

https://orcid.org/0000-0001-8677-993X

Eduardo Fabián Aragón Vásquez, Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia. Jerónimo Leiton y Gato Sobral. 170129. Quito, Ecuador

https://orcid.org/0000-0002-5142-0721

Renán Patricio Mena Pérez, Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia. Jerónimo Leiton y Gato Sobral. 170129. Quito, Ecuador

https://orcid.org/0000-0002-4560-4858

Jimmy Rolando Quisirumbay Gaibor, Universidad Central del Ecuador. Facultad de Medicina Veterinaria y Zootecnia. Jerónimo Leiton y Gato Sobral. 170129. Quito, Ecuador

 https://orcid.org/0000-0003-1612-8503

References

Campbell, J. M., Crenshaw, J. D., y Polo, J. (2013). The biological stress of early weaned piglets. Journal of animal science and biotechnology, 4(1), 1-4. https://doi.org/10.1186/2049-1891-4-19

Cunningham, J. G., y Klein, B. G. (2014). Fisiología veterinaria (5a ed.). Elsevier.

Escobar, J., Frank, J. W., Suryawan, A., Nguyen, H. V., Kimball, S. R., Jefferson, L. S., y Davis, T. A. (2005). Physiological rise in plasma leucine stimulates muscle protein synthesis in neonatal pigs by enhancing translation initiation factor activation. American Journal of Physiology-Endocrinology and Metabolism, 288(5), E914-E921. https://doi.org/10.1152/ajpendo.00510.2004

Escobar, J., Frank, J. W., Suryawan, A., Nguyen, H. V., Kimball, S. R., Jefferson, L. S., y Davis, T. A. (2006). Regulation of cardiac and skeletal muscle protein synthesis by individual branched-chain amino acids in neonatal pigs. American Journal of Physiology-Endocrinology and Metabolism, 290(4), E612-E621. https://doi.org/10.1152/ajpendo.00402.2005

HUMAN Gesellschatt Fur Biochemica and Diagnostica mbH. (2008). Manual de procedimientos. HUMAN. https://www.human.de/

Murgas Torrazza, R., Suryawan , A., Gazzaneo, M. C., Orellana, R. A., Frank, J. W., Nguyen, H. V., y Davis, T. A. (2010). Leucine supplementation of a low-protein meal increases skeletal muscle and visceral tissue protein synthesis in neonatal pigs by stimulating mTOR-dependent translation initiation. The Journal of Nutrition, 140(12), 2145-2152. https://doi.org/10.3945/jn.110.128421

National Research Council. (2012). Nutrient requirements of swine (11th ed.). National Academies Press. https://doi.org/10.17226/13298

Pluske, J. R., Hampson, D. J., y Williams, I. H. (1997). Factors influencing the structure and function of the small intestine in the weaned pig: a review. Livestock production science, 51(1-3), 215-236. https://doi.org/10.1016/S0301-6226(97)00057-2

Pluske, J. R., Turpin, D. L., y Kim, J. C. (2018). Gastrointestinal tract (gut) health in the young pig. Animal Nutrition, 4(2), 187-196. https://doi.org/10.1016/j.aninu.2017.12.004

Ren, M., Zhang, S. H., Zeng, X. F., Liu, H., y Qiao, S. Y. (2015). Branched-chain amino acids are beneficial to maintain growth performance and intestinal immune-related function in weaned piglets fed protein restricted diet. Asian-Australasian Journal of Animal Sciences, 28(12), 1742. https://doi.org/10.5713/ajas.14.0131

Suryawan, A., Murgas Torrazza, R., Gazzaneo, M. C., Orellana, R. A., Fiorotto, M. L., El-Kadi, S. W., y Davis, T. A. (2012). Enteral leucine supplementation increases protein synthesis in skeletal and cardiac muscles and visceral tissues of neonatal pigs through mTORC1-dependent pathways. Pediatric Research, 71(1), 324-331. https://doi.org/10.1038/pr.2011.79

Wang, J., Tan, B. E., Li, G. R., Xiao, H., Huang, B., Zhang, M. H., y Yin, Y. L. (2016). Polyamine metabolism in the intestine of piglets is altered by weaning and proline supplementation. Journal of Animal Science, 94(suppl_3), 423-428. https://doi.org/10.2527/jas.2015-9464

Wu, F., Xiong, X., Yang, H., Yao, K., Duan, Y., Wang, X., y Yin, Y. (2017). Expression of proteins in intestinal middle villus epithelial cells of weaning piglets. Frontiers in Bioscience-Landmark, 22(4), 539-557. https://doi.org/10.2741/4501

Wu, G., Wu, Z., Dai, Z., Yang, Y., Wang, W., Liu, C., y Yin, Y. (2013). Dietary requirements of “nutritionally non-essential amino acids” by animals and humans. Amino Acids, 44(4), 1107-1113. https://doi.org/10.1007/s00726-012-1444-2

Yang, H., Wang, X., Xiong, X., y Yin, Y. (2016a). Energy metabolism in intestinal epithelial cells during maturation along the crypt-villus axis. Scientific Reports, 6(1), 1-13. https://doi.org/10.1038/srep31917

Yang, H., Xiong, X., Wang, X., Tan, B., Li, T., y Yin, Y. (2016b). Effects of weaning on intestinal upper villus epithelial cells of piglets. PloS one, 11(3), e0150216. https://doi.org/10.1371/journal.pone.0150216

Yin, J., Ma, J., Li, Y., Ma, X., Chen, J., Zhang, H., y Yin, Y. (2020). Branched-chain amino acids, especially of leucine and valine, mediate the protein restricted response in a piglet model. Food & function, 11(2), 1304-1311. https://doi.org/10.1039/C9FO01757G

Yin, Y., Yao, K., Liu, Z., Gong, M., Ruan, Z., Deng, D., y Wu, G. (2010). Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. Amino Acids, 39(5), 1477-1486. https://doi.org/10.1007/s00726-010-0612-5

Zhang, S., Qiao, S., Ren, M., Zeng, X., Ma, X., Wu, Z., Thacker, P., y Wu, G. (2013). Supplementation with branched-chain amino acids to a low-protein diet regulates intestinal expression of amino acid and peptide transporters in weanling pigs. Amino Acids, 45(5), 1191-1205. https://doi.org/10.1007/s00726-013-1577-y

Zheng, L., Wei, H., Cheng, C., Xiang, Q., Pang, J., y Peng, J. (2016). Supplementation of branched-chain amino acids to a reduced-protein diet improves growth performance in piglets: involvement of increased feed intake and direct muscle growth-promoting effect. British Journal of Nutrition, 115(12), 2236-2245. https://doi.org/10.1017/S0007114516000842

Most read articles by the same author(s)